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The year 2024 was a landmark for the AI industry in the United States and globally.

According to our tally at TechCrunch, 49 startups secured funding rounds of $100 million or more in 2024. Notably, three companies obtained multiple “megarounds,” and seven companies received rounds exceeding $1 billion in size.

As we look ahead to 2025, it appears that the momentum from 2024 will continue. Although we are only halfway through the year, multiple billion-dollar rounds have already been announced, and the number of AI megarounds closed in the U.S. during Q1 2025 surpasses that of Q1 2024.

Below is a list of U.S. AI companies that have raised $100 million or more in 2025:

April

  • SandboxAQ completed a $450 million Series E round on April 4, valuing the AI model company at $5.7 billion. The round included notable investors such as Nvidia, Google, and Bridgewater Associates founder Ray Dalio.
  • Runway, a company specializing in AI models for media production, raised a $308 million Series D round announced on April 3, valuing the company at $3 billion. The round was led by General Atlantic, with participation from SoftBank, Nvidia, and Fidelity, among others.

March

  • AI giant OpenAI raised a record-breaking $40 billion funding round that valued the startup at $300 billion. This round, which closed on March 31, was led by SoftBank, with participation from Thrive Capital, Microsoft, and Coatue, among others.
  • On March 25, Nexthop AI, an AI infrastructure company, announced a Series A round led by Lightspeed Venture Partners. The $110 million round also included investments from Kleiner Perkins, Battery Ventures, and Emergent Ventures, among others.
  • Cambridge, Massachusetts-based Insilico Medicine raised $110 million for its generative AI-powered drug discovery platform, as announced on March 13. This Series E round valued the company at $1 billion and was co-led by Value Partners and Pudong Chuangtou.
  • AI infrastructure company Celestial AI raised a $250 million Series C round that valued the company at $2.5 billion. The March 11 round was led by Fidelity, with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
  • Lila Sciences raised a $200 million seed round as it aims to create a science superintelligence platform. The round was led by Flagship Pioneering, with funding also provided by March Capital, General Catalyst, and ARK Venture Fund, among others.
  • Brooklyn-based Reflection.Ai, which is developing superintelligent autonomous systems, raised a $130 million Series A round that values the 1-year-old company at $580 million. The round was led by Lightspeed Venture Partners and CRV.
  • AI coding startup Turing closed a Series E round on March 7 that valued the startup, which partners with LLM companies, at $2.2 billion. The $111 million round was led by Khazanah Nasional, with participation from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
  • Shield AI, an AI defense tech startup, raised $240 million in a Series F round that closed on March 6. This round was co-led by L3Harris Technologies and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Innovative Technology Fund, among others. The round valued the company at $5.3 billion.
  • AI research and large language model company Anthropic raised $3.5 billion in a Series E round that valued the startup at $61.5 billion. The round was announced on March 3 and was led by Lightspeed, with participation from Salesforce Ventures, Menlo Ventures, and General Catalyst, among others.

February

  • Together AI, which creates open source generative AI and AI model development infrastructure, raised a $305 million Series B round that valued the company at $3.3 billion. The February 20 round was co-led by Prosperity7 and General Catalyst, with participation from Salesforce Ventures, Nvidia, Lux Capital, and others.
  • AI infrastructure company Lambda raised a $480 million Series D round that was announced on February 19. The round valued the startup at nearly $2.5 billion and was co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Invest, and others also participated.
  • Abridge, an AI platform that transcribes patient-clinician conversations, was valued at $2.75 billion in a Series D round announced on February 17. The $250 million round
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