{"id":9174,"date":"2025-03-09T10:04:11","date_gmt":"2025-03-09T10:04:11","guid":{"rendered":"https:\/\/fusionmindlabs.com\/blogs\/scientists-discover-brain-activity-in-sleeping-people\/"},"modified":"2025-03-09T10:04:11","modified_gmt":"2025-03-09T10:04:11","slug":"scientists-discover-brain-activity-in-sleeping-people","status":"publish","type":"post","link":"https:\/\/fusionmindlabs.com\/blogs\/scientists-discover-brain-activity-in-sleeping-people\/","title":{"rendered":"Scientists Discover Brain Activity in Sleeping People"},"content":{"rendered":"\n<\/p>\n<p><strong>Uncovering the Secrets of Sleep: How Our Brains Remain Active During Rest<\/strong><\/p>\n<p>Though sleep is a time to power down and replenish our energy, our brains remain surprisingly active when we\u2019re at rest. In fact, more goes on behind our closed eyelids than we previously thought, according to a team of researchers that recently analyzed eye movements during slumber.<\/p>\n<p><strong>New Study Reveals Insights into Brain Activation During Sleep<\/strong><\/p>\n<p>In a <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-57289-5\" rel=\"nofollow noopener\" target=\"_blank\">study<\/a> published Wednesday in the journal Nature Communications, researchers in Switzerland analyzed the pupils of sleeping participants. The study reveals that our pupils constantly change size while we\u2019re unconscious, indicating different levels of <a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/brain-activation#:~:text=Brain%20activation%20refers%20to%20the,extracellular%20fluid%20through%20ion%20pumping.\" rel=\"nofollow noopener\" target=\"_blank\">brain activation<\/a>\u2014the brain\u2019s response to stimuli. With further research, doctors might one day use pupil activity to diagnose conditions such as sleep disorders.<\/p>\n<p><strong>Pupil Dynamics Reflect Brain Activation<\/strong><\/p>\n<p>Pupil dynamics \u201creflect the state of arousal, or the level of brain activation in regions that are responsible for sleep-wake regulation,\u201d said Caroline Lustenberger, a neuroscientist at ETH Z\u00fcrich and co-author of the study, in a university <a href=\"https:\/\/ethz.ch\/en\/news-and-events\/eth-news\/news\/2025\/03\/the-pupil-as-a-window-to-the-sleeping-brain.html\" rel=\"nofollow noopener\" target=\"_blank\">statement<\/a>. \u201cThese observations contradict the previous assumption that, essentially, the level of arousal during sleep is low.\u201d<\/p>\n<p><strong>Tracking Brain Activation During Sleep<\/strong><\/p>\n<p>The locus coeruleus\u2014a part of the brain that regulates activation levels\u2014is located in the brainstem and is notoriously difficult to study while individuals are asleep, according to the researchers. Since the pupil size is known to reflect brain activity, Lustenberger and her colleagues assumed they could also be used to track brain activation during sleep.<\/p>\n<p><strong>Innovative Method for Observing Eye Movements During Sleep<\/strong><\/p>\n<p>The team claims to be the first to observe eye movements during sleep for several hours at a time\u2014and I know what you\u2019re thinking: <em>how<\/em>? The featured image in this article is not a stock photo\u2014it shows how they actually did it. The researchers simply taped one eye of each participant open, moistened it with eye ointment, and then sealed it behind a transparent bandage.<\/p>\n<p><strong>Overcoming the Challenge of Sleeping with Eyes Open<\/strong><\/p>\n<p>\u201cOur main concern was that the test subjects would be unable to sleep with their eyes open. But in a dark room, most people forget that their eyes are still open and they are able to sleep,\u201d explained Manuel Carro Dom\u00ednguez, a biomedical engineer at ETH Z\u00fcrich and lead author of the study, who invented the technique.<\/p>\n<p><strong>Findings Confirm Constant Changes in Brain Activation During Sleep<\/strong><\/p>\n<p>Overall, the participants\u2019 pupil movement demonstrated that activation levels are constantly changing during sleep. According to the researchers, the finding confirms a biological feature in humans that <a href=\"https:\/\/www.nature.com\/articles\/s41583-020-0360-9\" rel=\"nofollow noopener\" target=\"_blank\">previous studies<\/a> had documented in rodents.<\/p>\n<p><strong>Link Between Pupil Dynamics and Brain Activity Patterns<\/strong><\/p>\n<p>The team also noted a link between pupil dynamics during sleep and specific brain activity patterns, including brain waves involved with sleep stability and memory consolidation. Furthermore, they discovered that the intensity of the brain\u2019s reaction to sound depends on the level of its activation, as indicated by the participants\u2019 pupils. However, the study did not prove whether the locus coeruleus directly influences pupil dynamics.<\/p>\n<p><strong>Future Research Directions<\/strong><\/p>\n<p>\u201cWe are simply observing pupil changes that are related to the level of brain activation and heart activity,\u201d Lustenberger explained. The team aims to investigate this potential dynamic, as well as how activation levels influence sleep, in a follow-up study. If they do find a strong causal relationship, pupil movement might one day be used to detect disorders such as insomnia and post-traumatic stress disorder, or even a <a href=\"https:\/\/gizmodo.com\/sleep-patterns-in-comatose-patients-may-predict-their-chances-of-waking-up-2000571376\" rel=\"nofollow noopener\" target=\"_blank\">comatose patient\u2019s recovery<\/a>.<\/p>\n<p><strong>Conclusion<\/strong><\/p>\n<p>We haven\u2019t yet figured out if eyes are windows to the soul\u2014but as the team\u2019s research shows, they\u2019re certainly windows to the brain!<\/p>\n\n<br \/><a href=\"https:\/\/gizmodo.com\/scientists-kept-peoples-eyes-open-while-they-slept-revealing-surprising-brain-activity-2000572533\" rel=\"nofollow noopener\" target=\"_blank\">Source Link<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Uncovering the Secrets of Sleep: How Our Brains Remain Active During Rest Though sleep is a time to power down and replenish our energy, our brains remain surprisingly active when&#8230;<\/p>\n","protected":false},"author":0,"featured_media":9175,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[220,2591,2892],"class_list":["post-9174","post","type-post","status-publish","format-standard","has-post-thumbnail","category-news","tag-neuroscience","tag-sleep","tag-sleep-disorders"],"jetpack_featured_media_url":"https:\/\/fusionmindlabs.com\/blogs\/wp-content\/uploads\/sites\/9\/2025\/03\/participant-with-pupil-technique.jpg","_links":{"self":[{"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/posts\/9174","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/comments?post=9174"}],"version-history":[{"count":0,"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/posts\/9174\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/media\/9175"}],"wp:attachment":[{"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/media?parent=9174"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/categories?post=9174"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fusionmindlabs.com\/blogs\/wp-json\/wp\/v2\/tags?post=9174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}